2025's 10 Best Travel-Safe Carry-On Backpacks - Ranked by Data

Flight-approved, laptop-friendly large travel backpack.

The WONHOX Large Travel Backpack is a versatile and robust travel accessory, designed to meet carry-on flight requirements. It features a laptop compartment, making it ideal for both work and travel purposes. The backpack is highly rated by customers for its durability, capacity, and comfort.

Extra-large, flight-approved backpack with organizing cubes.

The Lumesner 40L Backpack is a flight-approved, expandable carry-on designed for both men and women. It comes with 4 packing cubes for easy organization, and its extra-large capacity can accommodate all travel necessities.

Travel-friendly, stylish, and spacious LOVEVOOK backpack for women.

This is a spacious and stylish 40L backpack from LOVEVOOK, designed specifically for women. It is flight-approved and fits under the seat, making it perfect for business trips, weekend getaways, and other travels. The backpack has water-resistant properties and includes 2 cubes for better organization. It also has a special compartment which can fit a 17-inch laptop.

A flight-approved, 40L Carry-On Backpack perfect for convenient and efficient travel.

This 40L Carry-On Backpack in attractive purple color is specifically designed for hassle-free traveling. It is flight-approved, making it a perfect carry-on for most airlines. The backpack boasts a large capacity and is built with sturdy materials for durability.

Water-resistant, flight-approved backpack with a USB charging port and a laptop compartment.

This BAGSMART Travel Backpack is a versatile carry-on designed for convenience and durability. It can accommodate a laptop up to 17.3 inches and comes with a USB charging port. The backpack is also water-resistant, which enhances the protection of your belongings.

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A TSA-approved, water-resistant travel backpack, ideal for organizing your belongings during travel.

The BAGSMART Blast Travel Backpack is a durable, water-resistant weekender bag, designed for convenient travel. It is TSA approved as a personal carry on item, fitting up to a 15.6 inch laptop and includes several compartments for organized packing.

Waterproof, TSA-approved 40L backpack with three packing cubes.

The LOVEVOOK Travel Backpack is a high-quality, waterproof carry-on backpack that is perfect for both men and women. It has a capacity of 40L and comes with three packing cubes. It is airline approved and TSA-friendly, making it an ideal choice for frequent travelers.

MATEIN's expandable, water-resistant travel backpack is your perfect partner for weekend getaways and airplane travels.

This MATEIN 40L Travel Backpack is a durable, water-resistant bag designed for both men and women. It's expandable, airplane approved and perfect for use as a weekender bag or a carry-on for flights. Its key features include a lightweight design, multiple compartments for organization, and a comfortable, breathable back design.

A spacious, expandable TSA-approved carry-on backpack with a dedicated laptop compartment.

This large 50L carry-on backpack is TSA flight approved and features an expandable design from 40L to 50L, making it perfect for both short trips and long vacations. It includes a dedicated compartment for laptops and is made from durable, lightweight material ideal for business trips or weekend getaways.