Business Carry-On Backpacks Buying Guide: Best 10 for 2025

A TSA-friendly, water-resistant backpack with large storage and laptop compartment.

The tomtoc 40L Travel Backpack is a water-resistant, lightweight and durable bag designed for business travel. It features TSA-friendly design for smooth checkpoint experience, enough space for a 17.3-inch laptop and a large compartment for clothing and essential items. This PFAS-free backpack offers a unique combination of style, comfort, and utility.

Waterproof, anti-theft, flight-approved backpack that fits a 17-inch laptop and is ideal for business and leisure travels.

This large, flight-approved backpack is perfect for both business and leisure travels. It is equipped with anti-theft features, is waterproof, and can fit a 17-inch laptop, making it a versatile choice for various travel scenarios. It's designed to be a personal item size, so it's perfect for those who need a compact yet roomy travel companion.

Travel Backpack, 50L Expandable Extra Large Laptop Backpack, Carry On Backpack Water Resistant Busin

Amazon product: Travel Backpack, 50L Expandable Extra Large Laptop Backpack, Carry On Backpack Water Resistant Business Suitcase Daypack Bag Fits 17 Inch Laptops, Travel Gifts for Men Women, Black

Durable, stylish, and ScanSmart technology-enabled backpack for business travelers.

The SwissGear 1900 Scansmart TSA 17-inch Laptop Backpack is a durable, ergonomic, and stylish backpack designed for business travelers. It features a unique quick-recognition window designed to accommodate most 17-inch laptops and a ScanSmart lay-flat design for hassle-free laptop-in-bag TSA scanning.

Large, water-resistant laptop backpack with USB charger port and flight-approved design.

The MATEIN TSA Laptop Backpack is a versatile 17-inch backpack, perfect for travel and business use. It features a USB charger port, is water-resistant, and has a luggage sleeve for easy transportation. This backpack is approved for flight and is highly rated for its spaciousness and durability.

Tolaccea's TSA-friendly, spacious backpack for business travel with dual laptop and tablet storage.

The Tolaccea Travel Laptop Backpack is a versatile and spacious carry-on rucksack, perfect for business travel. It features an expandable compartment with dual storage for a 17.3" laptop and a 12.9" tablet, a TSA-friendly design for easy security checks, and an additional toiletry bag.

Waterproof business backpack with USB charging port and laptop compartment.

This smart and durable backpack from BANGE is designed for business travelers and it comfortably fits a 15.6-inch laptop. It features a built-in USB charging port, making it ideal for those on the go. The backpack also boasts of being water-resistant, providing extra protection for your belongings.

A durable, spacious, and versatile backpack for all types of travel.

This TSA-approved, 50L expandable travel backpack is a versatile, durable, and carry-on compatible solution for travelers. The backpack boasts a spacious main compartment, multiple storage pockets, and a separate laptop compartment that fits up to a 17-inch laptop. It is made of high-quality, water-resistant fabric and features a unique expandable design that increases its capacity when needed.

TSA-approved travel backpack with a USB charging port and a 17.3-inch laptop compartment.

The Taygeer Travel Backpack is a versatile bag designed for both men and women. It features a USB charging port, a shoe pouch, and a special compartment that can accommodate a 17.3-inch laptop. This TSA-approved backpack is perfect for business travel, hiking, and weekend trips.

Functional, secure 17-inch laptop backpack with USB charging port.

The Anti-Theft Laptop Backpack is a 17-inch backpack designed for men and suitable for business travels. It features an anti-theft design, a USB charging port, and is made from water-resistant material. This backpack also meets the requirements for carry-on luggage on flights, making it perfect for a work college weekender.