Search Categories

CFML PROCESSING: {ts '2025-12-13 11:54:11'}

We review products independently. We may earn a commission if you buy through our links, at no extra cost to you. Learn more


For more options, view the complete software list in our Cold Cough & Allergy section.

Antihistamines
Rose

Finding Relief: A Research Analyst's Take on the Best Antihistamines for Every Lifestyle Navigating the world of antihistamines can feel like searching for a needle in a haystack, especially when market research indicates that consumer preferences vary widely based on lifestyle and climate. Comparative analysis of product specifications shows that brands like Zyrtec and Claritin frequently receive positive ratings in customer reviews, often praised for their fast-acting relief and non-drowsy formulas. Interestingly, studies suggest that while generics can be just as effective, many consumers prefer name brands for their perceived reliability and consistent performance. Finding Relief: A Research Analyst's Take on the Best Antihistamines for Every Lifestyle Navigating the world of antihistamines can feel like searching for a needle in a haystack, especially when market research indicates that consumer preferences vary widely based on lifestyle and climate.

Similar Categories

Expert Score Breakdown

0.0 / 10
Excellent
1
Expert Score
9.5 / 10
313
31
BEST
HIGH POTENCY
PET ALLERGY RELIEF

Claritin Non-Drowsy Allergy Relief

Claritin Non-Drowsy Allergy Relief
860 reviews
Prescription-strength, 24-hour allergy relief tablets.
View Website
BEST
HIGH POTENCY
PET ALLERGY RELIEF

Why We Love It

Claritin Allergy Relief offers powerful, 24-hour relief from allergy symptoms. It's non-drowsy, allowing you to carry on with your day without feeling sluggish or tired. The large pack size of 70 tablets ensures you're covered for a considerable time.

Pros

  • 24-hour relief
  • Non-drowsy
  • Prescription strength
  • Convenient 70-count pack
  • Effective against various allergies

Cons

  • May not work for everyone
  • Potential side effects
  • Pricey compared to generic brands

Prescription-strength, 24-hour allergy relief tablets.

Claritin Allergy Medicine is a 24-hour, non-drowsy, prescription-strength allergy relief medication. The main active ingredient is Loratadine, a powerful antihistamine, and each pack contains 70 tablets.

Pros

  • 24-hour relief
  • Non-drowsy
  • Prescription strength
  • Convenient 70-count pack
  • Effective against various allergies

Cons

  • May not work for everyone
  • Potential side effects
  • Pricey compared to generic brands
BEST
HIGH POTENCY
PET ALLERGY RELIEF

Why We Love It

Claritin Allergy Relief offers powerful, 24-hour relief from allergy symptoms. It's non-drowsy, allowing you to carry on with your day without feeling sluggish or tired. The large pack size of 70 tablets ensures you're covered for a considerable time.

Pros

  • 24-hour relief
  • Non-drowsy
  • Prescription strength
  • Convenient 70-count pack
  • Effective against various allergies

Cons

  • May not work for everyone
  • Potential side effects
  • Pricey compared to generic brands

Why We Love It

Claritin Allergy Relief offers powerful, 24-hour relief from allergy symptoms. It's non-drowsy, allowing you to carry on with your day without feeling sluggish or tired. The large pack size of 70 tablets ensures you're covered for a considerable time.

Prescription-strength, 24-hour allergy relief tablets.

Claritin Allergy Medicine is a 24-hour, non-drowsy, prescription-strength allergy relief medication. The main active ingredient is Loratadine, a powerful antihistamine, and each pack contains 70 tablets.

2
Expert Score
7.9 / 10
279
98
BEST
BUDGET-FRIENDLY PACK

Zarbee's Children's All-in-One Honey Cough Syrup + Mucus, Throat & Nasal Day & Night Value Two Pack for Kids 6-12 + Dark Honey, Ivy Leaf Extract, Zinc Turmeric Root & B-Vitamins, Grape, 2 x 4 fl. Oz

Zarbee's Children's All-in-One Honey Cough Syrup + Mucus, Throat & Nasal Day & Night Value Two Pack for Kids 6-12 + Dark Honey, Ivy Leaf Extract, Zinc Turmeric Root & B-Vitamins, Grape, 2 x 4 fl. Oz
771 reviews
Zarbee's Children's All-in-One Honey Cough Syrup + Mucus, Throat & Nasal Day & Night Value Two Pack
View Website
BEST
BUDGET-FRIENDLY PACK

Why We Love It

Popular choice with good ratings

Pros

  • High quality
  • Reliable
  • Good value

Cons

  • Check reviews
  • Limited info

Zarbee's Children's All-in-One Honey Cough Syrup + Mucus, Throat & Nasal Day & Night Value Two Pack

Amazon product: Zarbee's Children's All-in-One Honey Cough Syrup + Mucus, Throat & Nasal Day & Night Value Two Pack for Kids 6-12 + Dark Honey, Ivy Leaf Extract, Zinc Turmeric Root & B-Vitamins, Grape, 2 x 4 fl. Oz

Pros

  • High quality
  • Reliable
  • Good value

Cons

  • Check reviews
  • Limited info
BEST
BUDGET-FRIENDLY PACK

Why We Love It

Popular choice with good ratings

Pros

  • High quality
  • Reliable
  • Good value

Cons

  • Check reviews
  • Limited info

Why We Love It

Popular choice with good ratings

Zarbee's Children's All-in-One Honey Cough Syrup + Mucus, Throat & Nasal Day & Night Value Two Pack

Amazon product: Zarbee's Children's All-in-One Honey Cough Syrup + Mucus, Throat & Nasal Day & Night Value Two Pack for Kids 6-12 + Dark Honey, Ivy Leaf Extract, Zinc Turmeric Root & B-Vitamins, Grape, 2 x 4 fl. Oz

3
Expert Score
7.8 / 10
119
40

Sudafed PE Children's Nasal Decongestant

Sudafed PE Children's Nasal Decongestant
26 reviews
Berry-flavored, effective nasal decongestant for children aged 4 and above.
View Website

Why We Love It

Sudafed PE Children's Nasal Decongestant is a trusted solution for relieving children's nasal congestion symptoms. Its pleasant berry flavor makes it easier for kids to take, and parents love it because it works fast to provide relief.

Pros

  • Effective congestion relief
  • Pleasant berry flavor
  • Suitable for children 4+

Cons

  • Not suitable for children under 4
  • May cause side effects
  • Requires correct dosage

Berry-flavored, effective nasal decongestant for children aged 4 and above.

Sudafed PE Children's Nasal Decongestant is a berry-flavored liquid medication, containing Phenylephrine HCl, designed to relieve nasal congestion symptoms in children. This 4 fl. oz bottle provides easy-to-take relief and is suitable for children aged 4 years and above.

Pros

  • Effective congestion relief
  • Pleasant berry flavor
  • Suitable for children 4+

Cons

  • Not suitable for children under 4
  • May cause side effects
  • Requires correct dosage

Why We Love It

Sudafed PE Children's Nasal Decongestant is a trusted solution for relieving children's nasal congestion symptoms. Its pleasant berry flavor makes it easier for kids to take, and parents love it because it works fast to provide relief.

Pros

  • Effective congestion relief
  • Pleasant berry flavor
  • Suitable for children 4+

Cons

  • Not suitable for children under 4
  • May cause side effects
  • Requires correct dosage

Why We Love It

Sudafed PE Children's Nasal Decongestant is a trusted solution for relieving children's nasal congestion symptoms. Its pleasant berry flavor makes it easier for kids to take, and parents love it because it works fast to provide relief.

Berry-flavored, effective nasal decongestant for children aged 4 and above.

Sudafed PE Children's Nasal Decongestant is a berry-flavored liquid medication, containing Phenylephrine HCl, designed to relieve nasal congestion symptoms in children. This 4 fl. oz bottle provides easy-to-take relief and is suitable for children aged 4 years and above.

4
Expert Score
7.7 / 10
471
11
BEST
BEST RELIABILITY
MOST LOVED CHOICE

Tylenol Children's Cold Relief

Tylenol Children's Cold Relief
6600 reviews
Multi-symptom children's cold medicine in grape-flavored liquid form.
View Website
BEST
BEST RELIABILITY
MOST LOVED CHOICE

Why We Love It

Tylenol Children's Cold Relief is loved for its comprehensive cold symptom relief for children. The grape flavor makes it easier for children to consume, and being a Tylenol product, it's a brand parents trust for their kids' health needs.

Pros

  • Multi-symptom relief
  • Contains Acetaminophen
  • Grape-flavored
  • Easy to consume
  • Trusted brand

Cons

  • Might cause drowsiness
  • Not suitable for certain health conditions

Multi-symptom children's cold medicine in grape-flavored liquid form.

Tylenol Children's Cold Relief is a multi-symptom relief medicine for children. It contains Acetaminophen for pain and fever relief, Chlorpheniramine Maleate as an antihistamine, and Dextromethorphan HBr as a cough suppressant. The medicine comes in a grape-flavored liquid form, making it easier for children to consume.

Pros

  • Multi-symptom relief
  • Contains Acetaminophen
  • Grape-flavored
  • Easy to consume
  • Trusted brand

Cons

  • Might cause drowsiness
  • Not suitable for certain health conditions
BEST
BEST RELIABILITY
MOST LOVED CHOICE

Why We Love It

Tylenol Children's Cold Relief is loved for its comprehensive cold symptom relief for children. The grape flavor makes it easier for children to consume, and being a Tylenol product, it's a brand parents trust for their kids' health needs.

Pros

  • Multi-symptom relief
  • Contains Acetaminophen
  • Grape-flavored
  • Easy to consume
  • Trusted brand

Cons

  • Might cause drowsiness
  • Not suitable for certain health conditions

Why We Love It

Tylenol Children's Cold Relief is loved for its comprehensive cold symptom relief for children. The grape flavor makes it easier for children to consume, and being a Tylenol product, it's a brand parents trust for their kids' health needs.

Multi-symptom children's cold medicine in grape-flavored liquid form.

Tylenol Children's Cold Relief is a multi-symptom relief medicine for children. It contains Acetaminophen for pain and fever relief, Chlorpheniramine Maleate as an antihistamine, and Dextromethorphan HBr as a cough suppressant. The medicine comes in a grape-flavored liquid form, making it easier for children to consume.

5
Expert Score
7.1 / 10
422
25
KID-FRIENDLY FLAVOR
ORGANIC INGREDIENTS

Genexa Kids' Cold & Flu Relief

Genexa Kids' Cold & Flu Relief
296 reviews
Organic, dye-free multi-symptom relief for children's cold and flu symptoms.
View Website
KID-FRIENDLY FLAVOR
ORGANIC INGREDIENTS

Why We Love It

We love this product because it's designed with kids' health in mind, using only organic ingredients and no artificial additives. The multi-symptom formula makes it a versatile choice for parents, and its pleasant blueberry flavor makes it easier for children to take.

Pros

  • Organic ingredients
  • No artificial additives
  • Multi-symptom relief
  • Pleasant blueberry flavor
  • Appropriate for ages 4-11

Cons

  • Only available in one flavor
  • May be too sweet for some children
  • Price may be high for some

Organic, dye-free multi-symptom relief for children's cold and flu symptoms.

Genexa Kids' Cold and Flu Relief is a 2-pack, multi-symptom, organic children's medicine. The formula is dye-free with 0% artificial additives and comes in a blueberry flavor, designed to relieve common cold and flu symptoms, including pain, fever, and cough for children aged 4 to 11.

Pros

  • Organic ingredients
  • No artificial additives
  • Multi-symptom relief
  • Pleasant blueberry flavor
  • Appropriate for ages 4-11

Cons

  • Only available in one flavor
  • May be too sweet for some children
  • Price may be high for some
KID-FRIENDLY FLAVOR
ORGANIC INGREDIENTS

Why We Love It

We love this product because it's designed with kids' health in mind, using only organic ingredients and no artificial additives. The multi-symptom formula makes it a versatile choice for parents, and its pleasant blueberry flavor makes it easier for children to take.

Pros

  • Organic ingredients
  • No artificial additives
  • Multi-symptom relief
  • Pleasant blueberry flavor
  • Appropriate for ages 4-11

Cons

  • Only available in one flavor
  • May be too sweet for some children
  • Price may be high for some

Why We Love It

We love this product because it's designed with kids' health in mind, using only organic ingredients and no artificial additives. The multi-symptom formula makes it a versatile choice for parents, and its pleasant blueberry flavor makes it easier for children to take.

Organic, dye-free multi-symptom relief for children's cold and flu symptoms.

Genexa Kids' Cold and Flu Relief is a 2-pack, multi-symptom, organic children's medicine. The formula is dye-free with 0% artificial additives and comes in a blueberry flavor, designed to relieve common cold and flu symptoms, including pain, fever, and cough for children aged 4 to 11.

6
Expert Score
6.4 / 10
381
17
LONG-LASTING RELIEF
TRUSTED BRANDS

Benadryl Dye-Free Allergy Liqui-Gels

Benadryl Dye-Free Allergy Liqui-Gels
12800 reviews
Fast-acting, dye-free allergy relief capsules by Benadryl.
View Website
LONG-LASTING RELIEF
TRUSTED BRANDS

Why We Love It

We love this product because it's a reliable and effective solution for allergy symptoms. Its dye-free formula is a great feature for those sensitive to dyes and the Liqui-Gel design makes it easy to take. Plus, it's affordable and made by Benadryl, a trusted name in allergy relief.

Pros

  • Fast allergy relief
  • Easy-to-swallow Liqui-Gels
  • Dye-free formula
  • Effective antihistamine
  • Affordable

Cons

  • May cause drowsiness
  • Not suitable for children

Fast-acting, dye-free allergy relief capsules by Benadryl.

Benadryl's Dye-Free Allergy Liqui-Gels are easy-to-swallow capsules that provide fast relief from allergy symptoms. Each capsule contains 25mg of Diphenhydramine HCl, an antihistamine that effectively combats symptoms such as sneezing, runny nose, and cold symptoms.

Pros

  • Fast allergy relief
  • Easy-to-swallow Liqui-Gels
  • Dye-free formula
  • Effective antihistamine
  • Affordable

Cons

  • May cause drowsiness
  • Not suitable for children
LONG-LASTING RELIEF
TRUSTED BRANDS

Why We Love It

We love this product because it's a reliable and effective solution for allergy symptoms. Its dye-free formula is a great feature for those sensitive to dyes and the Liqui-Gel design makes it easy to take. Plus, it's affordable and made by Benadryl, a trusted name in allergy relief.

Pros

  • Fast allergy relief
  • Easy-to-swallow Liqui-Gels
  • Dye-free formula
  • Effective antihistamine
  • Affordable

Cons

  • May cause drowsiness
  • Not suitable for children

Why We Love It

We love this product because it's a reliable and effective solution for allergy symptoms. Its dye-free formula is a great feature for those sensitive to dyes and the Liqui-Gel design makes it easy to take. Plus, it's affordable and made by Benadryl, a trusted name in allergy relief.

Fast-acting, dye-free allergy relief capsules by Benadryl.

Benadryl's Dye-Free Allergy Liqui-Gels are easy-to-swallow capsules that provide fast relief from allergy symptoms. Each capsule contains 25mg of Diphenhydramine HCl, an antihistamine that effectively combats symptoms such as sneezing, runny nose, and cold symptoms.

7
Expert Score
6.4 / 10
485
43
VALUE

Max Strength PE Decongestant

Max Strength PE Decongestant
862 reviews
Non-drowsy nasal decongestant for quick relief from sinus congestion.
View Website
VALUE

Why We Love It

This Max Strength PE Decongestant is a go-to for fast, non-drowsy relief from allergies and sinus congestion. It's high potency and the generous quantity in each pack make it a cost-effective option for ongoing use. Despite being a lesser-known brand, its effectiveness and affordability have earned it a high customer rating.

Pros

  • Non-drowsy formula
  • Fast relief for sinus congestion
  • Affordable
  • High potency
  • Large quantity pack

Cons

  • Brand not well-known
  • May not be suitable for everyone

Non-drowsy nasal decongestant for quick relief from sinus congestion.

Max Strength PE Phenylephrine HCl 10mg is a non-drowsy nasal decongestant designed to provide relief from allergy-induced sinus congestion. The product, which compares favorably with Sudafed PE Decongestant tablets, comes in a pack of 100 tablets. It's effective for adults seeking a quick and potent solution for allergies and sinus issues.

Pros

  • Non-drowsy formula
  • Fast relief for sinus congestion
  • Affordable
  • High potency
  • Large quantity pack

Cons

  • Brand not well-known
  • May not be suitable for everyone
VALUE

Why We Love It

This Max Strength PE Decongestant is a go-to for fast, non-drowsy relief from allergies and sinus congestion. It's high potency and the generous quantity in each pack make it a cost-effective option for ongoing use. Despite being a lesser-known brand, its effectiveness and affordability have earned it a high customer rating.

Pros

  • Non-drowsy formula
  • Fast relief for sinus congestion
  • Affordable
  • High potency
  • Large quantity pack

Cons

  • Brand not well-known
  • May not be suitable for everyone

Why We Love It

This Max Strength PE Decongestant is a go-to for fast, non-drowsy relief from allergies and sinus congestion. It's high potency and the generous quantity in each pack make it a cost-effective option for ongoing use. Despite being a lesser-known brand, its effectiveness and affordability have earned it a high customer rating.

Non-drowsy nasal decongestant for quick relief from sinus congestion.

Max Strength PE Phenylephrine HCl 10mg is a non-drowsy nasal decongestant designed to provide relief from allergy-induced sinus congestion. The product, which compares favorably with Sudafed PE Decongestant tablets, comes in a pack of 100 tablets. It's effective for adults seeking a quick and potent solution for allergies and sinus issues.

8
Expert Score
6.3 / 10
485
60
BEST RELIABILITY
MOST LOVED CHOICE
NON-DROWSY FORMULA
BUDGET-FRIENDLY

Fexofenadine 180mg Antihistamine 2 Pack

Fexofenadine 180mg Antihistamine 2 Pack
160 reviews
Non-drowsy antihistamine for relief from allergy symptoms.
View Website
BEST RELIABILITY
MOST LOVED CHOICE
NON-DROWSY FORMULA
BUDGET-FRIENDLY

Why We Love It

This antihistamine is loved for its effectiveness in alleviating allergy symptoms without causing drowsiness. Despite being a lesser-known brand, it is comparable to the widely recognized Allegra, but at a more affordable price point. Its large quantity also ensures longer use.

Pros

  • Effective allergy relief
  • Non-drowsy formula
  • Comparable to Allegra
  • Affordable
  • Large quantity

Cons

  • Brand unknown
  • May not work for everyone

Non-drowsy antihistamine for relief from allergy symptoms.

Fexofenadine Hydrochloride 180mg antihistamine is an effective over-the-counter medication that offers relief from various allergy symptoms such as hives, runny nose, and itching. It is a non-drowsy formula, making it ideal for daytime use. This product is comparable to the popular Allegra 24 Hour Non-Drowsy Allergy Medicine.

Pros

  • Effective allergy relief
  • Non-drowsy formula
  • Comparable to Allegra
  • Affordable
  • Large quantity

Cons

  • Brand unknown
  • May not work for everyone
BEST RELIABILITY
MOST LOVED CHOICE
NON-DROWSY FORMULA
BUDGET-FRIENDLY

Why We Love It

This antihistamine is loved for its effectiveness in alleviating allergy symptoms without causing drowsiness. Despite being a lesser-known brand, it is comparable to the widely recognized Allegra, but at a more affordable price point. Its large quantity also ensures longer use.

Pros

  • Effective allergy relief
  • Non-drowsy formula
  • Comparable to Allegra
  • Affordable
  • Large quantity

Cons

  • Brand unknown
  • May not work for everyone

Why We Love It

This antihistamine is loved for its effectiveness in alleviating allergy symptoms without causing drowsiness. Despite being a lesser-known brand, it is comparable to the widely recognized Allegra, but at a more affordable price point. Its large quantity also ensures longer use.

Non-drowsy antihistamine for relief from allergy symptoms.

Fexofenadine Hydrochloride 180mg antihistamine is an effective over-the-counter medication that offers relief from various allergy symptoms such as hives, runny nose, and itching. It is a non-drowsy formula, making it ideal for daytime use. This product is comparable to the popular Allegra 24 Hour Non-Drowsy Allergy Medicine.

9
Expert Score
6.2 / 10
347
12
NATURAL INGREDIENTS

Histamine Shield Plus Antihistamine

Histamine Shield Plus Antihistamine
650 reviews
Natural antihistamine supplement for effective sinus and allergy relief.
View Website
NATURAL INGREDIENTS

Why We Love It

We love this product because of its natural and potent ingredients, offering a non-drowsy solution to allergy and sinus problems. Many users appreciate its effectiveness against a variety of allergens, making it a versatile choice for those seeking relief.

Pros

  • Natural ingredients
  • Effective for various allergens
  • Non-drowsy formula
  • Ample supply with 120 capsules

Cons

  • Relatively expensive
  • May not work for everyone

Natural antihistamine supplement for effective sinus and allergy relief.

Histamine Shield Plus is a natural antihistamine supplement designed to relieve sinus and allergy symptoms caused by pollen, pet dander, dust, mold, and odors. The formula contains Quercetin with Bromelain and Stinging Nettle, providing 120 capsules per package.

Pros

  • Natural ingredients
  • Effective for various allergens
  • Non-drowsy formula
  • Ample supply with 120 capsules

Cons

  • Relatively expensive
  • May not work for everyone
NATURAL INGREDIENTS

Why We Love It

We love this product because of its natural and potent ingredients, offering a non-drowsy solution to allergy and sinus problems. Many users appreciate its effectiveness against a variety of allergens, making it a versatile choice for those seeking relief.

Pros

  • Natural ingredients
  • Effective for various allergens
  • Non-drowsy formula
  • Ample supply with 120 capsules

Cons

  • Relatively expensive
  • May not work for everyone

Why We Love It

We love this product because of its natural and potent ingredients, offering a non-drowsy solution to allergy and sinus problems. Many users appreciate its effectiveness against a variety of allergens, making it a versatile choice for those seeking relief.

Natural antihistamine supplement for effective sinus and allergy relief.

Histamine Shield Plus is a natural antihistamine supplement designed to relieve sinus and allergy symptoms caused by pollen, pet dander, dust, mold, and odors. The formula contains Quercetin with Bromelain and Stinging Nettle, providing 120 capsules per package.

10
Expert Score
6.0 / 10
315
39

Major 4mg Allergy Relief Tablets

Major 4mg Allergy Relief Tablets
448 reviews
Effective 4-hour antihistamine tablets for allergy relief.
View Website

Why We Love It

The Major Allergy Tablets provide affordable and effective relief from allergy symptoms for long periods. The bulk packaging makes this product a cost-effective solution for those who suffer from allergies regularly.

Pros

  • Effective for allergy relief
  • Long-lasting 4-hour effectiveness
  • Bulk package for long term use

Cons

  • Brand unknown
  • May cause drowsiness in some users

Effective 4-hour antihistamine tablets for allergy relief.

Major Allergy Tablets contain Chlorpheniramine Maleate, a powerful antihistamine that provides up to 4 hours of relief from allergy symptoms such as runny nose, sneezing, itching of the nose or throat, and itchy, watery eyes. This product comes in a bulk package of 1,000 tablets, offering long-term use for allergy sufferers.

Pros

  • Effective for allergy relief
  • Long-lasting 4-hour effectiveness
  • Bulk package for long term use

Cons

  • Brand unknown
  • May cause drowsiness in some users

Why We Love It

The Major Allergy Tablets provide affordable and effective relief from allergy symptoms for long periods. The bulk packaging makes this product a cost-effective solution for those who suffer from allergies regularly.

Pros

  • Effective for allergy relief
  • Long-lasting 4-hour effectiveness
  • Bulk package for long term use

Cons

  • Brand unknown
  • May cause drowsiness in some users

Why We Love It

The Major Allergy Tablets provide affordable and effective relief from allergy symptoms for long periods. The bulk packaging makes this product a cost-effective solution for those who suffer from allergies regularly.

Effective 4-hour antihistamine tablets for allergy relief.

Major Allergy Tablets contain Chlorpheniramine Maleate, a powerful antihistamine that provides up to 4 hours of relief from allergy symptoms such as runny nose, sneezing, itching of the nose or throat, and itchy, watery eyes. This product comes in a bulk package of 1,000 tablets, offering long-term use for allergy sufferers.

Product Comparison

Product Active Ingredient
1 Claritin Non-Drowsy Allergy Relief
Loratadine
2 Sudafed PE Children's Nasal Decongestant
Phenylephrine HCl
3 Tylenol Children's Cold Relief
Acetaminophen
4 Genexa Kids' Cold & Flu Relief
Organic ingredients
5 Benadryl Dye-Free Allergy Liqui-Gels
Diphenhydramine HCl
6 Max Strength PE Decongestant
Phenylephrine
7 Fexofenadine 180mg Antihistamine 2 Pack
Fexofenadine
8 Histamine Shield Plus Antihistamine
Natural
9 Major 4mg Allergy Relief Tablets
Chlorpheniramine
10 Allegra 24 Hour Allergy Relief
Fexofenadine
11 ValuMeds 24-Hour Allergy Caplets
Cetirizine
12 Allegra Kids 12-Hour Allergy Relief
Fexofenadine HCl
13 Benadryl Children's Allergy Relief Liquid
Diphenhydramine HCl
14 Robitussin Elderberry Child's Cough Syrup
Elderberry
15 Benadryl Children's Allergy Relief
Diphenhydramine HCl
16 24-Hour Allergy Relief Tablets
Cetirizine
17 A+Health Cetirizine Allergy Tablets
Cetirizine HCl
18 ValuMeds 24-Hour Allergy Relief
Fexofenadine Hydrochloride
19 ValuMeds 24-Hour Allergy Relief
Loratadine
20 Puregen Labs Non-Drowsy Allergy Relief
Fexofenadine
21 Delsym Cough Relief Combo Pack
Dextromethorphan
22 Basic Care Night Cold & Flu
Acetaminophen
23 Beekeeper's Kids Nighttime Cough Syrup
Propolis, Elderberry
24 HealthA2Z Fexofenadine Allergy Relief
Fexofenadine Hydrochloride
25 Natural Allergy Relief Tablets
Quercetin
26 Benadryl Allergy & Cold Relief
Diphenhydramine HCl
27 HealthA2Z Kids' Allergy Relief
Fexofenadine Hydrochloride
28 Amazon Basic Care Children's Allergy Relief
Cetirizine Hydrochloride
29 Boiron Allergy & Sinus Relief
Histaminum 30C
30 Member's Mark Allergy Loratadine Tablets
Loratadine
31 MAJOR 4 Mg Allergy Tablets
Chlorpheniramine Maleate
32 MAJOR 4 Mg Allergy Tablets
Chlorpheniramine Maleate
33 Zyrtec 24hr Allergy Relief Tablets
Cetirizine HCl
34 Zarbee's Children's All-in-One Honey Cough Syrup + Mucus, Throat & Nasal Day & Night Value Two Pack
Honey, Ivy Leaf Extract
1

Claritin Non-Drowsy Allergy Relief

Active Ingredient
Loratadine
2

Sudafed PE Children's Nasal Decongestant

Active Ingredient
Phenylephrine HCl
3

Tylenol Children's Cold Relief

Active Ingredient
Acetaminophen
4

Genexa Kids' Cold & Flu Relief

Active Ingredient
Organic ingredients
5

Benadryl Dye-Free Allergy Liqui-Gels

Active Ingredient
Diphenhydramine HCl
6

Max Strength PE Decongestant

Active Ingredient
Phenylephrine
7

Fexofenadine 180mg Antihistamine 2 Pack

Active Ingredient
Fexofenadine
8

Histamine Shield Plus Antihistamine

Active Ingredient
Natural
9

Major 4mg Allergy Relief Tablets

Active Ingredient
Chlorpheniramine
10

Allegra 24 Hour Allergy Relief

Active Ingredient
Fexofenadine
11

ValuMeds 24-Hour Allergy Caplets

Active Ingredient
Cetirizine
12

Allegra Kids 12-Hour Allergy Relief

Active Ingredient
Fexofenadine HCl
13

Benadryl Children's Allergy Relief Liquid

Active Ingredient
Diphenhydramine HCl
14

Robitussin Elderberry Child's Cough Syrup

Active Ingredient
Elderberry
15

Benadryl Children's Allergy Relief

Active Ingredient
Diphenhydramine HCl
16

24-Hour Allergy Relief Tablets

Active Ingredient
Cetirizine
17

A+Health Cetirizine Allergy Tablets

Active Ingredient
Cetirizine HCl
18

ValuMeds 24-Hour Allergy Relief

Active Ingredient
Fexofenadine Hydrochloride
19

ValuMeds 24-Hour Allergy Relief

Active Ingredient
Loratadine
20

Puregen Labs Non-Drowsy Allergy Relief

Active Ingredient
Fexofenadine
21

Delsym Cough Relief Combo Pack

Active Ingredient
Dextromethorphan
22

Basic Care Night Cold & Flu

Active Ingredient
Acetaminophen
23

Beekeeper's Kids Nighttime Cough Syrup

Active Ingredient
Propolis, Elderberry
24

HealthA2Z Fexofenadine Allergy Relief

Active Ingredient
Fexofenadine Hydrochloride
25

Natural Allergy Relief Tablets

Active Ingredient
Quercetin
26

Benadryl Allergy & Cold Relief

Active Ingredient
Diphenhydramine HCl
27

HealthA2Z Kids' Allergy Relief

Active Ingredient
Fexofenadine Hydrochloride
28

Amazon Basic Care Children's Allergy Relief

Active Ingredient
Cetirizine Hydrochloride
29

Boiron Allergy & Sinus Relief

Active Ingredient
Histaminum 30C
30

Member's Mark Allergy Loratadine Tablets

Active Ingredient
Loratadine
31

MAJOR 4 Mg Allergy Tablets

Active Ingredient
Chlorpheniramine Maleate
32

MAJOR 4 Mg Allergy Tablets

Active Ingredient
Chlorpheniramine Maleate
33

Zyrtec 24hr Allergy Relief Tablets

Active Ingredient
Cetirizine HCl
34

Zarbee's Children's All-in-One Honey Cough Syrup + Mucus, Throat & Nasal Day & Night Value Two Pack

Active Ingredient
Honey, Ivy Leaf Extract

Similar Categories

Chewable Antihistamines
Chewable Antihistamines
Children's Antihistamines
Children's Antihistamines
Nasal Spray Antihistamines
Nasal Spray Antihistamines
Liquid Antihistamines
Liquid Antihistamines
Non-Drowsy Antihistamines
Non-Drowsy Antihistamines

How We Rank Products

Our Evaluation Process

In the evaluation of antihistamines, the methodology focuses on several key factors, including active ingredients, dosing options, side effects, and duration of efficacy. Specific considerations such as the type of allergy relief provided (e.g., seasonal vs. year-round), the age appropriateness of the product, and user convenience factors like dosage form (tablets, liquids, etc.) significantly influence the selection process. Rankings are determined by analyzing comprehensive data from customer reviews and ratings, along with a comparison of product specifications and price-to-value ratios, ensuring a thorough assessment of each product's effectiveness and overall value in the market. This approach aims to provide consumers with clear, research-based insights into the best antihistamine options available.

Verification

  • Products evaluated through comprehensive research and analysis of ingredient efficacy.
  • Selection criteria focus on safety profiles and user satisfaction ratings of antihistamines.
  • Comparison methodology analyzes customer feedback and expert reviews to highlight the most effective options.

As an Amazon Associate, we earn from qualifying purchases. We may also earn commissions from other affiliate partners.

Frequently Asked Questions About Antihistamines

What makes a antihistamines the "best"?

We evaluate products based on quality, performance, value for money, user reviews, durability, and ease of use. Our rankings are updated regularly to reflect the latest market offerings and user feedback.

How often do you update your antihistamines recommendations?

Our team continuously monitors the market for new products and updates our recommendations quarterly. We also adjust rankings based on user feedback and new testing results.

Do you test all the products you recommend?

Yes, whenever possible, we physically test products in our labs. For products we can't test directly, we rely on verified user reviews, expert opinions, and detailed specifications to make informed recommendations.

What if I'm looking for a specific type of antihistamines?

Our top 10 list covers the most popular and highly-rated options. If you have specific requirements, check our detailed product descriptions and pros/cons to find the best match for your needs.

×

Price History

Loading price history...

Curated By

What This Award Means